VAT and Customs Duties for International Shipping

[axntdsgn]

We're building out a new VM site with the intention of selling products (small data loggers) worldwide, to perhaps 100 countries on all continents. The company is based in the USA, but the current plan is to ship everything from Europe (Germany or Belgium most likely).

The question is how to calculate VAT, Sales Tax and customs duties. I believe Avalara could handle the VAT/Sales Tax, but it's not clear if that's the case. We could use TaxCloud for USA, and build VAT tax rules for other countries, but not sure if that's the best route for accuracy and maintainability. For customs duty calculations, not sure if shipping plugins (FedEx, UPS, etc) also calculate customs duties for international shipping.

Does anyone have experience in setting up VM site for international sales?