At http://www.OpenSourceSupportdesk.com (http://www.opensourcesupportdesk.com) we used the JA Edenite template for its beautiful and neat design and VirtueMart for eCommerce.
We have made several small changes to the default template layout by adding 5 module positions below the main menu and by changing the font to Arial, that's all.
For the Online Helpdesk, which uses a dedicated system, we created a unique design based on JA Edenite to embed the system seamlessly in a wrapper.
For VirtueMart we implemented a few small changes in the category browse pages.
The respons we get is great. Obviously we would like to hear any type of feedback from other Joomla- and VirtueMart-users.
I love thhose there image icon at the bottom of the mainPage. Cool ;)