Tax rule and Shipping rule question.

[gifts.wine]

I am somewhat new to all this.

Tax rule and Shipping rule question.

My Tax Question:

Can I set up different rules in Virtuemart to charge a certain % based on the customers zip code? Some states and counties my customer has to charge tax where others he does not have to.

My Shipping Question:

My customer only ships in the lower 48 states. I have been able to set up shipping by the price of an order but this is not how my customer is looking for this to work.

I see that Virtuemart can be set up to ship by weight and zip code? I am having a hard time getting this right for whatever reason. 

My customer has over 500 products with all different weights.

Do I have to enter a weight range for each zip code range sense of course it's cheaper to ship 2 pounds to a zip code 10 miles away verses 1 pound 2500 miles away.

Or

Can virtuemart be set up to use a customer's UPS account so all the zip codes and weights will calculate through it properly as long as the proper weight and sizes are added to the products backend ?

Or is there an extension or mod out there I would need to accomplish this?

Thank You in Advance for any Help I can get on this PLEASE